International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats

The Veterinary Journal, Volume 247, May 2019, Pages 8-25
J. Scott Weese, Joseph Blondeaub, Dawn Boothe, Luca Guardabassi, Nigel Gumley, Mark Papich, Lisbeth Rem Jessen, Michael Lappin, Shelley Rankin, Jodi L.Westropp, Jane Sykes

Highlights

  • These guidelines provide recommendations for the diagnosis and management of bacterial urinary tract infections in dogs and cats.
  • Sporadic bacterial cystitis, recurrent bacterial cystitis, pyelonephritis, bacterial prostatitis, and subclinical bacteriuria are addressed.
  • Issues pertaining to urinary catheters, medical dissolution of uroliths and prophylaxis for urological procedures are discussed.

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Hope for the Diet-Related Dilated Cardiomyopathy Dilemma

Canine Health Foundation 06/01/2022

For several years, scientists have been investigating the increase in reported cases of dilated cardiomyopathy (DCM) in dog breeds without a genetic predisposition to this disease. Other factors such as toxin exposure, infectious agents, and/or nutrition could contribute to disease development in these dogs, but diet has received the most attention. Learn more

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Outbreak of Severe Vomiting in Dogs Associated with a Canine Enteric Coronavirus, United Kingdom

Outbreak of Severe Vomiting in Dogs Associated with a Canine Enteric Coronavirus, United Kingdom; Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 27, No.2 February, 2021 Click Here

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The first genome-wide association study concerning idiopathic epilepsy in Petit Basset Griffon Vendeen

The first genome-wide association study concerning idiopathic epilepsy in Petit Basset Griffon Vendeen by T Deschain, J Fabricius, M Berendt, M Fredholm, P Karlskov-Mortensen; August 2021

*Department of Veterinary and Animal Sciences, Animal Genetics, Bioinformatics & Breeding, University of Copenhagen, Gronnegaardsvej 3, Frederiksberg C DK-1870, Denmark. †Section for Surgery, Neurology & Cardiology, Faculty of Health and Medical Sciences, University Hospital for Companion Animals, University of Copenhagen, Dyrlægevej 16, Frederiksberg C DK-1870, Denmark

Summary
The dog breed Petit Basset Griffon Vendeen has a relatively high prevalence of idiopathic epilepsy compared to other dog breeds and previous studies have suggested a genetic cause of the disease in this breed. Based on these observations, a genome-wide association study was performed to identify possible epilepsy-causing loci. The study included 30 unaffected and 23 affected dogs, genotyping of 170K SNPs, and data analysis using PLINK and EMMAX. Suggestive associations at CFA13, CFA24 and CFA35 were identified with markers close to three strong candidate genes. However, subsequent sequencing of exons of the three genes did not reveal sequence variations, which could explain development of the disease. This is, to our knowledge, the first report on loci and genes with a possible connection to idiopathic epilepsy in Petit Basset Griffon Vendeen. However, further studies are needed to conclusively identify the genetic cause of idiopathic epilepsy in this dog breed.

Keywords dog, epilepsy, genome-wide association study, Petit Basset Griffon Vendeen

Full Article Click Link:  The first genome-wide association study concerning idiopathic epilepsy in PBGV

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Duration of immunity after rabies vaccination in dogs: The Rabies Challenge Fund research study

The Rabies Challenge Fund’s research study has been made available in entirety to the public.

The goal of the fund was to extend mandated rabies booster intervals to 5 or 7 years and help reduce the risk of vaccine-associated adverse events. Read more…

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A Clinical Trial of Medium-Chain Triglyceride Oil for the Treatment of Canine Epilepsy

Author: Sharon M. Albright, DVM, CCRT Source: AKC Canine Health Foundation
5/6/2020

Despite appropriate treatment with anti-seizure medications, one-third of epileptic dogs continue to have seizures. The side effects of anti-seizure medications and the behavioral changes that often accompany canine epilepsy (anxiety and cognitive decline) lead to a decreased quality of life for affected dogs and their owners. For these reasons and more, the AKC Canine Health Foundation (CHF) and its donors are investing in research to explore new treatment options for canine epilepsy. Read more

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Breeding Soundness Examination of the Bitch

By Carla Barstow, DVM*, Robyn R. Wilborn, DVM, MS, Aime K. Johnson, DVM, 2018

KEY POINTS
* A thorough physical examination done at the beginning of a bitch’s breeding career may help identify any abnormalities that may cause a problem in the future.
* Obtaining an accurate history is important to guide diagnostic testing and future breeding management.
* Interpret diagnostic results with respect to the patient. Results should be examined as a whole and not as individual parts.

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Understanding Canine Epilepsy

Understanding Canine Epilepsy
Canine Health Foundation, June 2014
Introduction
Epilepsy is the most common neurological disease seen in dogs, affecting up to five percent of the canine population (3,4). However, this statistic is somewhat misleading as epilepsy is not a single disease. Instead, the diagnosis of epilepsy potentially refers to any one of a number of conditions that are characterized by the presence of chronic, recurring seizures. These conditions may be inherited (genetic, primary or idiopathic epilepsy), caused by structural problems in the brain (structural or secondary epilepsy), result from metabolic problems or a toxic exposure (reactive epilepsy), or stem from an unknown cause (4). Determination of an appropriate treatment regimen for canine epilepsy depends on an accurate diagnosis of the type and cause of seizures, only after which appropriate therapeutic options can be identified. Read full article

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